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1 edition of Toxicology and Carcinogenesis Studies of Pentachloroanisole (Cas No. 1825-21-4) in F344/N Rats, Technical Report Series, No. 414, U.S. Department of Health and Human Services, 1995. found in the catalog.

Toxicology and Carcinogenesis Studies of Pentachloroanisole (Cas No. 1825-21-4) in F344/N Rats, Technical Report Series, No. 414, U.S. Department of Health and Human Services, 1995.

Toxicology and Carcinogenesis Studies of Pentachloroanisole (Cas No. 1825-21-4) in F344/N Rats, Technical Report Series, No. 414, U.S. Department of Health and Human Services, 1995.

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Published .
Written in English


Edition Notes

ContributionsNational Cancer Institute (U.S.)
ID Numbers
Open LibraryOL15513809M

14 PREFACE Medical Toxicology of Natural Substances: Foods, Fungi, The following provides organizational details on the Medicinal Herbs, Plants, and Venomous Animals is material under the headings for each toxin: designed to provide in-depth, evidence-based coverage of the most important natural toxins. This book is the History provides. National Toxicology Program (NTP) () Toxicology and carcinogenesis studies of pentachloroanisole (CAS No –21–4) in F/N rats and B6C3F1 mice. Google Scholar National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, by: IUPAC TOXICOLOGY FOUNDATION COURSE ESSENTIAL TOXICOLOGY An Educational Resource Prepared by John H. Duffus1* and Howard G.J. Worth2 1The Edinburgh Centre for Toxicology, 43 Mansionhouse Road, Edinburgh EH9 2JD, Scotland, U.K. 2Clinical Chemistry Department, King's Mill Centre for Health Care Services, Mansfield Road, Sutton-in-Ashfield, .


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Toxicology and Carcinogenesis Studies of Pentachloroanisole (Cas No. 1825-21-4) in F344/N Rats, Technical Report Series, No. 414, U.S. Department of Health and Human Services, 1995. Download PDF EPUB FB2

Get this from a library. NTP technical report on the toxicology and carcinogenesis studies of pentachloroanisole (CAS No. ) in F/N rats and B6C3F₁ mice (gavage studies).

[National Toxicology Program (U.S.);]. TOXICOLOGY. AND. CARCINOGENESIS STUDIES OF. QUERCETIN (CASNO. ) IN. F/N. RATS (FEED. STUDIES) U.S. DEPART" OF HEALTH AND HUMAN SERVICES PublicHealth Service National Institutes of Health.

FOREWORD The National Toxicology Program (NTP) is made up of four charter agencies of the U.S. Department of Health andFile Size: 9MB. Toxicology & Carcinogenesis Studies of Pentachloroanisole in F/N Rats and B6C3F1 Mice (Feed Studies). Technical Report Series No.

() NIH Publication No. U.S. Department of Health and Human Services, National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC Toxicology and carcinogenesis studies of pentachloronitrobenzene (99% pure), a fungicide, were con- ducted by administering diets containing 0,2, or 5, ppm pentachloronitrobenzene to groups of 50 B6C3F1 mice of each sex for weeks.

These doses were selected because, in week studies in. NTP Toxicology and Carcinogenesis Studies of 1,3-Butadiene (CAS No. ) in B6C3F1 Mice (Inhalation Studies). National Toxicology Program. 1,3-Butadiene is used as an intermediate in the production of elastomers, polymers, and other chemicals.

Of the 1,3-butadiene used in Toxicology and Carcinogenesis Studies of Pentachloroanisole book, 44% was used to manufacture styrene-butadiene rubber (a. 1. Toxicology. Jun 1;(1) Inhalation toxicology and carcinogenesis studies of propylene glycol mono-t-butyl ether in rats and mice. Doi AM(1), Roycroft JH, Herbert RA, Haseman JK, Hailey JR, Chou BJ, Dill JA, Toxicology and Carcinogenesis Studies of Pentachloroanisole book SL, Miller RA, Renne RA, Bucher by: 7.

The Center for Molecular Toxicology and Carcinogenesis (CMTC) was formed in to develop and expand programs in toxicology and carcinogenesis at Penn State. Over the past twenty-two years, the center has fostered the development of interdisciplinary research programs as well as graduate and undergraduate programs in toxicology.

The studies described in this Technical Report were performed under the direction of the NIEHS and indicator of a chemical’s carcinogenic potential. bases of human exposure, level of production, and chemical structure.

Toxicology and Carcinogenesis Studies of Pentachloroanisole book per se is not an mice). Chemicals selected for NTP toxicology and carcinogenesis studies are chosen primarily on the. Therefore, additional toxicology and carcinogenesis studies were conducted in F/N rats by administering hexachloroethane (approximately 99% pure) in corn oil by gavage to groups of males and females for 16 days, 13 weeks, or 2 years.

Genetic toxicology studies Toxicology and Carcinogenesis Studies of Pentachloroanisole book conducted in Salmonella typhimurium and in Chinese hamster ovary (CHO) cells. Full text of "NTP technical report on the toxicology and carcinogenesis studies of ethylene glycol (CAS no.

) in B6C3F́ mice (feed studies)" See other formats. Toxicology and Carcinogenesis Studies of p,p'-Dichlorodiphenyl Sulfone in Rats and Mice Article (PDF Available) in Toxicological Sciences 60(1).

Toxicology and Carcinogenesis Studies of Ozone and Ozone 4-(N-Nitrosomethylamino)(3-Pyridyl)Butanone in Fischer/N Rats Article (PDF Available) in. t -Butyl alcohol is widely used in the manufacture of perfumes and a variety of cosmetics.

It is also used as a raw material in the production of isobutylene, which may be used to produce methyl tertiary butyl ether, a common gasoline additive, or to produce butyl elastomers used in the production of automobile tires. McGregor, D.B., Martin, R., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J.

Responses of the LY tk+/tk- mouse lymphoma cell forward mutation assay to. Table 8–1 lists definitions of terms commonly used in discussing chemical carcinogenesis.

For benign neoplasms, the tissue of origin is frequently followed by the suffix “oma”; for example, a benign fibrous neoplasm would be termed fibroma, and a benign glandular epithelium termed an adenoma.

Malignant neoplasms from epithelial origin are called carcinomas, whereas those. National Toxicology Program; Availability of Technical Report on Toxicology and Carcinogenesis Studies of 3,4-Dihydrocoumarin An Uncategorized Document by the Health and Human Services Department on 09/16/ FUNDAMENTAL AND APPLIED TOXICOL () Toxicology and Carcinogenesis Studies of Two Grades of Pentachlorophenol in B6C3F1 Mice E.

MCCONNELL,I'* J. HUFF,* M. HEJTMANCIK,t A. PETERS,' AND R. PERSINGt *National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Cited by: Cover title: Toxicology and carcinogenesis studies of naphthalene.

This banner text can have markup. TOXICOLOGY AND CARCINOGENESIS STUDIES OF PENT ACHLORONITROBENZENE (CAS NO. ) IN B6C3Ft MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P Box Research Triangle Park, NC January NTP TR NIH Publication No. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service.

Several excellent reviews of the historical background of carcinogenesis and cancer research have been published (Creech, ; Diamandopoulos, ; Shimkin, ).

Studies over the last three centuries on chemically induced cancer are marked initially by epidemiological observations followed by experimental studies involving animal.

Their studies demonstrate that a novel life-saving strategy can be developed by targeting death protein sPLA2 and Wnt/ß-catenin pathway to rescue the APAP-overdosed patients. Dadhania feels that his graduate studies at the ULM have provided a solid toxicology background with exceptional research training.

Este es el único estudio realizado en seres vivos para evaluar el potencial toxicológico y cancerígeno del compuesto 4-Metilidimadazol que se encuentra en el c.

TOXICOLOGY AND APPLIED PHARMACOL () Studies on the Disposition and Metabolism of Pentachloroanisole in Female Mice MARY JO VODICNIK,* ANDREW H. GLICKMAN,* DOUGLAS E. RICKERT,t AND JOHN J. LECH* * Department of Pharmacology and Toxicology, The Medical College of Wisconsin, Milwaukee, Wisconsinand tChemical Cited by: 7.

The third edition of the Encyclopedia of Toxicology presents entries devoted to key concepts and specific chemicals, and is updated to reflect current advances in the field. It contains new information on nanotoxicology, epigenetics, persistent organic pollutants, computational toxicology and bioinformatics, controversial chemicals, and much more.

Adhere to ever-changing regulations with our Pentachloroanisole reference standards for environmental testing, CAS number: Buy online at LGC Standards. We use cookies to ensure that we give you the best experience of our website. About MyAccess. If your institution subscribes to this resource, and you don't have a MyAccess Profile, please contact your library's reference desk for information on how to gain access to this resource from off-campus.

Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required /5(2).

Encyclopedia of Toxicology, Volume 4, Second Edition 2nd Edition by Philip Wexler (Editor) ISBN Author: Philip Wexler. al Toxicology Program.

Toxicology and Carcinogenesis Studies of 2-Chloroacetophenone (CAS No. ) in F/N Rats and B6C3F 1 Mice (Inhalation Studies). TR No. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, Bethesda, MD.

4.U.S. Environmental Protection Agency. Pentachlorophenol (PCP) and pentachloroanisole (PCA) were rapidly taken up by rainbow trout when the concentrations of these compounds in water were μg/ml.

Following a 24 hr exposure of trout to 14 C-PCP the liver, blood, fat and muscle contaiand μg/g PCP, by: Pentachloroanisole is a chlorinated aromatic compound, which is widely distributed at low levels in the environment. It is the main degradation product of pentachlorophenol (PCP) and pentachloronitrobenzene.

This is the common definition for Pentachloroanisole PCA, other definitions can be discussed in the article. Tools to minimize interlaboratory variability in vitellogenin gene expression monitoring programs; Species-specific metabolism of naphthalene and phenanthrene in 3 species of marine teleosts exposed to Deepwater Horizon crude oil.

Approvable. The non-clinical studies with pazaponib support the safety of its use in renal cell carcinoma. Recommendation for nonclinical studies No additional non-clinical studies are required for pazopanib C. Recommendations on labeling The recommendations to the sponsor’s proposed labeling are given, with a.

The EUROTOX Molecular Toxicology Specialty Section organised an inaugural course on molecular toxicology at Ege University, Izmir, Turkey, June Recent developments in science and feedback from various parties made this educational meeting a much anticipated and well attended event.

Environmental Toxicology Assessment of heavy metal and PAH exposure in largemouth bass (Micropterus salmoides) in the Reedy River watershed, South Carolina, USA: A multi‐season assessment of metallothionein and bile fluorescence.

This book is a compilation of experimentally determined solubility ranges of over 1, compounds in the National Toxicology Program's Chemical Repository. Each compound's solubility was determined in a consistent manner in one to six solvents.

Solvents chosen were those most commonly used for toxi. Structure, properties, spectra, suppliers and links for: MFCD, STUDY AREA 6 - TOXICOLOGY/ CARCINOGENICITY NEW/UPDATE since February Entry No.

STUDY TITLE SOURCE STATUS COMPLETION DATE SUMMARY OF AIMS OF STUDY SUMMARY OF MAIN carcinogenesis France / French Food Safety Agency (AFSSA) O December The aims of the study were reconsidered: a short term rat.

Adhere to ever-changing regulations with our Pentachloroanisole reference standards for environmental testing, CAS number: Buy online at LGC Standards. U.S. NTP Acute Toxicity Studies View Studies Cholinesterase Inhibitor: II, Moderately Hazardous Not Listed Not Available Slightly to Moderately Toxic No 2.

The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. Pdf (PCP) has been shown to be methylated to O-methyl-PCP, pentachloroanisole (PCA), in various biological systems.

Pdf disposition and metabolism of PCA were studied in female mice to which the compound was administered at a dose of 20 mg (14C)PCA/kg. Elimination of (14C)PCA equivalents from mouse tissues was rapid, with half .Editor's note: Some chemicals in this database contain more information than others due to the original reason download pdf information was collected and how the compilation was accomplished.

While working with material safety data sheets (MSDS), I found that manufacturers sometimes used obscure names for constituent chemicals and I didn't always have a good idea of what I was .Ebook book will provide concise practical guidance for those wishing to apply these methods (in risk / hazard assessment) and will be illustrated with case studies.

Chemical Toxicity Prediction is the first book that addresses the concept of category formation and Author: Mark T. D. Cronin, Judith Madden, Steven Enoch.